- Hyperhidrosis is considered more detrimental to daily function and more difficult to conceal than many other dermatologic conditions; current treatments are minimally effective, inconvenient and/or uncomfortable.
- In the United States alone, there are about 11 million people suffering from primary focal hyperhidrosis and over half of them remain undiagnosed or have not discussed their condition with a healthcare professional. In addition, there are about 7 million people suffering from secondary hyperhidrosis.
- The most commonly prescribed treatments tend to be antiperspirants. While these products may temporarily help with mild symptoms, their application tends to be limited by modest efficacy especially in cases suffering from moderate to severe hyperhidrosis.
- While muscarinic antagonists have demonstrated efficacy in clinical trials, they have significant side effects, most commonly dry mouth, which decreases patient compliance with treatment resulting in poor clinical outcomes.
Overall, given the limitations of options available in the market today, we believe there is a significant unmet need in a large patient population.